Pharmacist-Led Diagnostics: A New Frontier in Antimicrobial Stewardship
<b>Background:</b> Antimicrobial resistance (AMR) is accelerating globally, driven by widespread inappropriate antibiotic use and diagnostic uncertainty in primary care. Pharmcist-led point-of-care testing (POCTs) has emerged as a promising model to optimize antibiotic prescribing, improve triage, and strengthen antimicrobial stewardship (AMS). <b>Methods:</b> This scoping review synthesizes current evidence, regulatory models, and implementation data on pharmacist-led diagnostics and antibiotic management across multiple countries. <b>Results:</b> Despite strong policy interest, clinical trial evidence remains limited. Existing studies-primarily pilots, feasibility work, and service evaluations-suggest that POCTs combined with structured pathways reduces inappropriate antibiotic use. <b>Conclusions:</b> Regulatory fragmentation, workforce limitations, and insufficient monitoring systems constrain widespread implementation. Larger, well-designed trials are needed to establish long-term safety, clinical outcomes, and AMS impact.
Authors
- Greta Kaspute (ORCID: https://orcid.org/0009-0002-0605-3317)
- Tatjana Ivaškienė (ORCID: https://orcid.org/0000-0003-2064-6792)
Institutions
- State Research Institute Centre for Innovative Medicine (LT)
Publication Details
- Journal
- Antibiotics
- Published
- 2025-12-18
- DOI
- https://doi.org/10.3390/antibiotics14121286
- Primary Topic
- Antibiotic Use and Resistance
- Type
- article
- Field-Weighted Citation Impact
- 0.00