Genomic and Phenotypic Landscape of Antibiotic Resistance in Gut Lactic Acid Bacteria from Livestock Environments
This study provides a detailed phenotypic and genomic insight into antibiotic resistance in gut-derived LAB from livestock. The findings highlight that commensal LAB can harbor clinically relevant ARGs-sometimes on mobile genetic elements-without always expressing corresponding resistance phenotypes. Such LAB may serve as a hidden reservoir for antibiotic resistance, raising the risk of ARG dissemination through the food chain. These results underscore the importance of vigilant monitoring and genomic screening of LAB, especially those considered for use in foods or feed, to ensure they do not contribute to the spread of antimicrobial resistance.
Authors
- Justyna Nasiłowska (ORCID: https://orcid.org/0000-0002-9114-2615)
- Anna Mikołajczuk-Szczyrba (ORCID: https://orcid.org/0000-0002-7445-2849)
- Adrian Wojtczak (ORCID: https://orcid.org/0009-0005-5428-0815)
- Ewelina Jaroszewska
- Joanna Bucka-Kolendo (ORCID: https://orcid.org/0000-0002-8082-1153)
- Paulina Średnicka (ORCID: https://orcid.org/0000-0001-8597-301X)
- Dziyana Shymialevich (ORCID: https://orcid.org/0000-0002-2474-283X)
- Agnieszka Zapaśnik (ORCID: https://orcid.org/0000-0002-5492-8352)
- Hanna Cieślak
- Karolina Wnęk-Auguścik (ORCID: https://orcid.org/0000-0002-3200-2743)
Institutions
- Warsaw University of Life Sciences (PL)
- Institute of Agricultural and Food Biotechnology (PL)
Publication Details
- Journal
- Genes
- Published
- 2025-12-18
- DOI
- https://doi.org/10.3390/genes16121518
- Citations
- 1
- Primary Topic
- Probiotics and Fermented Foods
- Type
- article
- Field-Weighted Citation Impact
- 1.16