Real-world Evaluation of Histoplasmosis Diagnosis and Treatment in Patients From a Michigan Health System

In a cohort of patients with histoplasmosis from Michigan, variation in diagnostic testing and treatment was observed. Most patients were diagnosed by positive tissue histopathology and itraconazole was the most frequently prescribed antifungal followed by posaconazole. Opportunities for more sensitive diagnostic testing and improved antifungal dose optimization and monitoring were identified.

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Publication Details

Journal
Open Forum Infectious Diseases
Published
2025-11-26
DOI
https://doi.org/10.1093/ofid/ofaf694
Primary Topic
Fungal Infections and Studies
Type
article
Field-Weighted Citation Impact
0.00
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article

Real-world Evaluation of Histoplasmosis Diagnosis and Treatment in Patients From a Michigan Health System

Lisa E. Dumkow, Andrew Jameson, Kamah Ellena, Ryan Tomlin et al.
Open Forum Infectious Diseases
Fungal Infections and Studies
article

Real-world Evaluation of Histoplasmosis Diagnosis and Treatment in Patients From a Michigan Health System

Lisa E. Dumkow, Andrew Jameson, Kamah Ellena, Ryan Tomlin, Noah D Blower
article en

Abstract

In a cohort of patients with histoplasmosis from Michigan, variation in diagnostic testing and treatment was observed. Most patients were diagnosed by positive tissue histopathology and itraconazole was the most frequently prescribed antifungal followed by posaconazole. Opportunities for more sensitive diagnostic testing and improved antifungal dose optimization and monitoring were identified.

Open Forum Infectious DiseasesVol. 12(12)
Grand Rapids Community College (US), Trinity Health (US), Marietta Memorial Hospital (US), Michigan State University (US)
Openalex Percentile: Top 47%
Fungal Infections and Studies
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