Iron Deficiency Associated Thrombocytosis May Reach Very High Levels in Children and Usually Shows Inverse Correlation with Hemoglobin and MCV: Report of a Pediatric Case and a Brief Literature Review
In this report, we describe the case of a child with iron deficiency anemia associated with markedly elevated platelet count. We provide detailed sequential data showing platelet count correction towards normal levels as anemia improved with treatment. We discuss the association between iron deficiency and thrombocytosis, the role of IL-6, the potential interaction with other variables such as infections and possible serious complications such as thrombosis.
Authors
- Kathleen Nicol (ORCID: https://orcid.org/0000-0002-2028-8465)
- Basil M. Kahwash (ORCID: https://orcid.org/0000-0002-6468-7230)
- Samir B. Kahwash (ORCID: https://orcid.org/0000-0001-8944-2128)
- Roopa Kodimyala (ORCID: https://orcid.org/0000-0003-4013-8461)
Institutions
- Nationwide Children's Hospital (US)
- ENT and Allergy (US)
- The Ohio State University (US)
Publication Details
- Journal
- Pediatric and Developmental Pathology
- Published
- 2025-12-18
- DOI
- https://doi.org/10.1177/10935266251404130
- Primary Topic
- Platelet Disorders and Treatments
- Type
- article
- Field-Weighted Citation Impact
- 0.00