EHF as a key regulator mediating cell migration and may contribute to tumor immune infiltration and progression in human endometrial cancer
Elevated EHF expression in EC patients correlated with diminished immune cell infiltration and a worse outcome. Decreasing EHF levels also affected the invasion and proliferation of EC cells. These findings highlight EHF as a putative prognostic and diagnostic biomarker for EC.
Authors
- Yi You (ORCID: https://orcid.org/0000-0003-3436-2133)
- Tsung Wai Kan (ORCID: https://orcid.org/0009-0001-0013-8486)
- Ling Yuan
- Xiaoqing Yang (ORCID: https://orcid.org/0000-0003-4592-682X)
- Xudong Chen (ORCID: https://orcid.org/0000-0002-0135-0606)
- Xinyi Chen (ORCID: https://orcid.org/0009-0002-4912-8905)
- Zhou Liu (ORCID: https://orcid.org/0000-0002-7169-0382)
- Xiaoyi Ding
Institutions
- Nantong University (CN)
- Affiliated Hospital of Nantong University (CN)
- Shanghai University of Medicine and Health Sciences (CN)
- Wuxi People's Hospital (CN)
Publication Details
- Journal
- BMC Cancer
- Published
- 2025-12-18
- DOI
- https://doi.org/10.1186/s12885-025-15447-4
- Primary Topic
- Immunotherapy and Immune Responses
- Type
- article
- Field-Weighted Citation Impact
- 0.00