Diagnosis, treatment management, and challenges in neurofibromatosis type 1: a case report with mixed features
In conclusion, the clinical management of pediatric NF1 patients is complex as therapeutic interventions are not for all. Due to heterogeneous manifestations and variable disease trajectories, there is no standardized treatment algorithm. Integrating molecular diagnostics, targeted therapies, and multidisciplinary care is crucial for personalized and effective long - term management of those with this genetic disorder.
Authors
- Xianan Zhang
- Youwei Ai (ORCID: https://orcid.org/0000-0002-2698-623X)
- Wei Luo (ORCID: https://orcid.org/0000-0002-8800-4422)
- Xiao Yang (ORCID: https://orcid.org/0000-0002-2351-4827)
- Lin Zhang
- Chen Jiang (ORCID: https://orcid.org/0009-0007-2109-0235)
- Yan Liu (ORCID: https://orcid.org/0000-0002-7894-121X)
Institutions
- Jinan University (CN)
- Zhuhai People's Hospital (CN)
Publication Details
- Journal
- Annals of Medicine and Surgery
- Published
- 2025-12-18
- DOI
- https://doi.org/10.1097/ms9.0000000000004521
- Primary Topic
- Neurofibromatosis and Schwannoma Cases
- Type
- article
- Field-Weighted Citation Impact
- 0.00