Beyond weight loss: tirzepatide as a dual GIP/GLP-1 receptor agonist for obstructive sleep apnea

As a dual GIP/GLP-1 RA, tirzepatide represents a promising therapy for OSA in individuals with obesity, offering benefits of both weight reduction and symptom improvement. Given the high burden and underdiagnosis of OSA, particularly in populations with obesity, it should be considered earlier in the treatment algorithm, either in combination with or as an alternative to traditional therapies.

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Publication Details

Journal
Current Opinion in Endocrinology Diabetes and Obesity
Published
2025-12-17
DOI
https://doi.org/10.1097/med.0000000000000949
Primary Topic
Obstructive Sleep Apnea Research
Type
article
Field-Weighted Citation Impact
0.00
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article

Beyond weight loss: tirzepatide as a dual GIP/GLP-1 receptor agonist for obstructive sleep apnea

Jairo Noreña, Tugce Akcan, Dimpi Desai
Current Opinion in Endocrinology Diabetes and Obesity
Obstructive Sleep Apnea Research
article

Beyond weight loss: tirzepatide as a dual GIP/GLP-1 receptor agonist for obstructive sleep apnea

Jairo Noreña, Tugce Akcan, Dimpi Desai
article en

Abstract

As a dual GIP/GLP-1 RA, tirzepatide represents a promising therapy for OSA in individuals with obesity, offering benefits of both weight reduction and symptom improvement. Given the high burden and underdiagnosis of OSA, particularly in populations with obesity, it should be considered earlier in the treatment algorithm, either in combination with or as an alternative to traditional therapies.

Current Opinion in Endocrinology Diabetes and Obesity
Alameda Health System (US), Stanford Medicine (US), Stanford University (US)
Openalex Percentile: Top 50%
Obstructive Sleep Apnea Research
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