Real-World Experience with Anti-CGRP Pathway Monoclonal Antibodies in a Large United States Healthcare Plan: Results of the Migraine Signature Study

Among patients who dispensed ≥ 1 anti-CGRP mAb for migraine, rates of sustained treatment over the course of a year were higher than expected; ~ 75% continued their index mAb at 6 months and > 50% at 12 months. Patients using anti-CGRP mAbs at the time of the survey reported higher satisfaction than patients who had discontinued anti-CGRP mAb.

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Publication Details

Journal
Neurology and Therapy
Published
2025-12-17
DOI
https://doi.org/10.1007/s40120-025-00872-1
Primary Topic
Migraine and Headache Studies
Type
article
Field-Weighted Citation Impact
0.00

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article

Real-World Experience with Anti-CGRP Pathway Monoclonal Antibodies in a Large United States Healthcare Plan: Results of the Migraine Signature Study

Richard B. Lipton, Sarah Robinson, Alice Jacobson, Dawn C. Buse et al.
Neurology and Therapy
Migraine and Headache Studies
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Real-World Experience with Anti-CGRP Pathway Monoclonal Antibodies in a Large United States Healthcare Plan: Results of the Migraine Signature Study

Richard B. Lipton, Sarah Robinson, Alice Jacobson, Dawn C. Buse, Shruti Vaidya, Alexandra Scott, Robert Urman, Alice Pressman, Mark Bensink
article en

Abstract

Among patients who dispensed ≥ 1 anti-CGRP mAb for migraine, rates of sustained treatment over the course of a year were higher than expected; ~ 75% continued their index mAb at 6 months and > 50% at 12 months. Patients using anti-CGRP mAbs at the time of the survey reported higher satisfaction than patients who had discontinued anti-CGRP mAb.

Neurology and TherapyVol. 15(1)
Sutter Health (US), Albert Einstein College of Medicine (US), Amgen (United States) (US), Montefiore Medical Center (US), Kaiser Permanente (US)
Amgen
Openalex Percentile: Top 52%
Migraine and Headache Studies
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