7-Hydroxyethyl Chrysin Alleviates High Altitude Pulmonary Edema via Activation of the PI3K/AKT Signaling Pathway

These findings indicate that 7-HEC may mitigate HAPE by activating the PI3K/AKT signaling pathway and could serve as an effective agent for preventing HAPE.

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Publication Details

Journal
Drug Design Development and Therapy
Published
2025-12-01
DOI
https://doi.org/10.2147/dddt.s541390
Primary Topic
Flavonoids in Medical Research
Type
article
Field-Weighted Citation Impact
0.00
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article

7-Hydroxyethyl Chrysin Alleviates High Altitude Pulmonary Edema via Activation of the PI3K/AKT Signaling Pathway

Xin Yu, Gege Wang, Linlin Jing, Ning Wang et al.
Drug Design Development and Therapy
Flavonoids in Medical Research
article

7-Hydroxyethyl Chrysin Alleviates High Altitude Pulmonary Edema via Activation of the PI3K/AKT Signaling Pathway

Xin Yu, Gege Wang, Linlin Jing, Ning Wang, Huiping Ma
article en

Abstract

These findings indicate that 7-HEC may mitigate HAPE by activating the PI3K/AKT signaling pathway and could serve as an effective agent for preventing HAPE.

Drug Design Development and TherapyVol. Volume 19
82th Hospital of Pla (CN), First Affiliated Hospital of Xi'an Jiaotong University (CN)
Openalex Percentile: Top 56%
Flavonoids in Medical Research
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