Comparable real‐world effectiveness between switches to cabotegravir + rilpivirine long‐acting or modern daily oral regimens in the United States: an OPERA cohort study

In the United States, routine clinical care, CVF risk did not differ between a switch to CAB+RPV LA or new oral ART, with most individuals remaining on their regimens at study end. Lower CD4 count at initiation was the only predictor of CVF on CAB+RPV LA.

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Publication Details

Journal
Journal of the International AIDS Society
Published
2025-12-01
DOI
https://doi.org/10.1002/jia2.70068
Primary Topic
Virus-based gene therapy research
Type
article
Field-Weighted Citation Impact
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article

Comparable real‐world effectiveness between switches to cabotegravir + rilpivirine long‐acting or modern daily oral regimens in the United States: an OPERA cohort study

Michael Sension, Jennifer S Fusco, Jean van Wyk, Michael Wohlfeiler et al.
Journal of the International AIDS Society
Virus-based gene therapy research
article

Comparable real‐world effectiveness between switches to cabotegravir + rilpivirine long‐acting or modern daily oral regimens in the United States: an OPERA cohort study

Michael Sension, Jennifer S Fusco, Jean van Wyk, Michael Wohlfeiler, Brooke Levis, Quateka Cochran, Laurence Brunet, Vani Vannappagari, Gregory Fusco, Gayathri Sridhar, Ricky K Hsu
article en

Abstract

In the United States, routine clinical care, CVF risk did not differ between a switch to CAB+RPV LA or new oral ART, with most individuals remaining on their regimens at study end. Lower CD4 count at initiation was the only predictor of CVF on CAB+RPV LA.

Journal of the International AIDS SocietyVol. 28(12)
AIDS Healthcare Foundation (US), Henderson Behavioral Health (US), NYU Langone Health (US), ViiV Healthcare (United Kingdom) (GB), GridBridge (United States) (US)
Openalex Percentile: Top 57%
Virus-based gene therapy research
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Comparable real‐world effectiveness between switches to cabotegravir + rilpivirine long‐acting or modern daily oral regimens in the United States: an OPERA cohort study — Michael Sension, Jennifer S Fusco, et al. · Journal of the International AIDS Society (2025) | TGRS Research Map | TGRS