Immune Imbalance and Dynamic Characteristics of T Helper 17, Regulatory T, and Regulatory B Cells in Children With Persistent Immune Thrombocytopenia
Both Th17/Treg cell imbalance and Breg cell deficiency contribute to the pathogenesis of persistent ITP in children. Concurrent monitoring of these immune subsets may aid in immunophenotyping, and their potential role as biomarkers for treatment outcomes warrants further investigation.
Authors
- Zhiyin Wang
- Fangmin Zhang (ORCID: https://orcid.org/0000-0003-1419-3117)
- Rui Fan (ORCID: https://orcid.org/0000-0001-6757-9422)
- Shujun Li (ORCID: https://orcid.org/0009-0000-9153-5323)
- Xuyang Dai
- Guo Jia (ORCID: https://orcid.org/0000-0003-3936-0006)
- Bao Liu (ORCID: https://orcid.org/0000-0001-6359-959X)
- Peiling Li
- Yuanfei Wang (ORCID: https://orcid.org/0000-0002-5561-7038)
- Zhihang Wang (ORCID: https://orcid.org/0000-0002-0826-3628)
Institutions
- First Affiliated Hospital of Xinxiang Medical University (CN)
- Henan Medical University (CN)
Publication Details
- Journal
- Pediatric Blood & Cancer
- Published
- 2025-12-17
- DOI
- https://doi.org/10.1002/1545-5017.70067
- Primary Topic
- Platelet Disorders and Treatments
- Type
- article
- Field-Weighted Citation Impact
- 0.00