Deep learning for imaging diagnosis of jaw cystic lesions and maxillofacial tumors: A narrative review

Deep learning continues to advance imaging-based diagnosis in oral and maxillofacial radiology. This narrative review has synthesized recent deep learning applications for detecting, classifying, and segmenting jaw cystic lesions and maxillofacial tumors on panoramic radiographs and cone-beam computed tomography scans. It has summarized representative one-stage detectors and convolutional neural network/transformer-based classifiers, along with segmentation methods, reported performance metrics, and key use-case considerations. In addition to this synthesis, the review has critically examined dataset constraints, spectrum and site bias, device-related heterogeneity, annotation inconsistency, and gaps in model explainability as well as described how these limitations restrict generalizability. Practical considerations for clinical implementation are also discussed, including workflow placement, quality assurance, and governance, followed by emerging research directions such as federated learning, multimodal fusion, and radiomics-deep learning combinations, each evaluated in terms of feasibility and current evidence maturity. Key evaluation metrics are interpreted in the context of dental imaging. Overall, current findings suggest that deep learning may enhance early and consistent recognition of jaw lesions, support surgical planning through automated delineation, and promote standardized interpretation, provided that models undergo external validation, reporting remains transparent, and deployment is guided by appropriate clinical oversight.

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Publication Details

Journal
Journal of International Medical Research
Published
2025-12-01
DOI
https://doi.org/10.1177/03000605251404778
Primary Topic
Dental Radiography and Imaging
Type
article
Field-Weighted Citation Impact
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article

Deep learning for imaging diagnosis of jaw cystic lesions and maxillofacial tumors: A narrative review

Bolun Zhang, Changkui Liu, Jingyi Shi, Yuan Li et al.
Journal of International Medical Research
Dental Radiography and Imaging
article

Deep learning for imaging diagnosis of jaw cystic lesions and maxillofacial tumors: A narrative review

Bolun Zhang, Changkui Liu, Jingyi Shi, Yuan Li, Su Liu
article en

Abstract

Deep learning continues to advance imaging-based diagnosis in oral and maxillofacial radiology. This narrative review has synthesized recent deep learning applications for detecting, classifying, and segmenting jaw cystic lesions and maxillofacial tumors on panoramic radiographs and cone-beam computed tomography scans. It has summarized representative one-stage detectors and convolutional neural network/transformer-based classifiers, along with segmentation methods, reported performance metrics, and key use-case considerations. In addition to this synthesis, the review has critically examined dataset constraints, spectrum and site bias, device-related heterogeneity, annotation inconsistency, and gaps in model explainability as well as described how these limitations restrict generalizability. Practical considerations for clinical implementation are also discussed, including workflow placement, quality assurance, and governance, followed by emerging research directions such as federated learning, multimodal fusion, and radiomics-deep learning combinations, each evaluated in terms of feasibility and current evidence maturity. Key evaluation metrics are interpreted in the context of dental imaging. Overall, current findings suggest that deep learning may enhance early and consistent recognition of jaw lesions, support surgical planning through automated delineation, and promote standardized interpretation, provided that models undergo external validation, reporting remains transparent, and deployment is guided by appropriate clinical oversight.

Journal of International Medical ResearchVol. 53(12)
Shanxi Medical University (CN), Shaanxi Provincial People's Hospital (CN), First Affiliated Hospital of Xi'an Jiaotong University (CN), Stomatology Hospital (CN), Guizhou Provincial People's Hospital (CN), Shanxi Provincial People’s Hospital (CN)
Openalex Percentile: Top 44%
Dental Radiography and Imaging
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