Menopausal hormone therapy and the risk of breast cancer in women with a pathogenic variant in <i>BRCA1</i> or <i>BRCA2</i>
Our findings suggest there is no significant increase in the risk of breast cancer in BRCA carriers with the use of MHT and that E alone might be protective.
Authors
- Nadine Tung
- Fergus J. Couch (ORCID: https://orcid.org/0000-0001-9417-9985)
- Teresa Ramón y Cajal (ORCID: https://orcid.org/0000-0003-3490-3585)
- Kelly Metcalfe (ORCID: https://orcid.org/0000-0003-1803-2169)
- Jan Lubiński (ORCID: https://orcid.org/0000-0003-2931-3003)
- Tomasz Huzarski (ORCID: https://orcid.org/0000-0003-3857-4854)
- William D. Foulkes (ORCID: https://orcid.org/0000-0001-7427-4651)
- Louise Bordeleau (ORCID: https://orcid.org/0000-0003-2111-0228)
- Tuya Pal (ORCID: https://orcid.org/0000-0001-8009-2475)
- Amber M. Aeilts (ORCID: https://orcid.org/0000-0001-8907-7853)
- Dana Zakalik (ORCID: https://orcid.org/0000-0002-6212-7942)
- Marta Seca (ORCID: https://orcid.org/0000-0003-1944-0842)
- Raymond H. Kim (ORCID: https://orcid.org/0000-0002-2147-8674)
- Robert Fruscio (ORCID: https://orcid.org/0000-0001-5688-2194)
- Andrea Eisen (ORCID: https://orcid.org/0000-0001-8037-9556)
- Beth Y. Karlan (ORCID: https://orcid.org/0000-0002-9451-2933)
- Cezary Cybulski (ORCID: https://orcid.org/0000-0002-2819-3057)
- Joanne Kotsopoulos (ORCID: https://orcid.org/0000-0001-9624-4218)
- Pål Møller (ORCID: https://orcid.org/0000-0001-8211-8237)
- Christian F. Singer
- Jacek Gronwald
- Steven A Narod
- Susan L. Neuhausen
- Ping Sun
- Olufunmilayo Olopade
Institutions
- Oslo University Hospital (NO)
- Beth Israel Deaconess Medical Center (US)
- Sunnybrook Health Science Centre (CA)
- University Health Network (CA)
- Mayo Clinic (US)
- 3M (United States) (US)
- Johns Hopkins University (US)
- University of California, Los Angeles (US)
- Oakland University (US)
- University of Toronto (CA)
- Beaumont Health (US)
- Juravinski Cancer Centre (CA)
- Norwegian Cancer Society (NO)
- McGill University Health Centre (CA)
- Hospital de Sant Pau (ES)
- Women's College Hospital (CA)
- Princess Margaret Cancer Centre (CA)
- The Ohio State University Wexner Medical Center (US)
- University of Chicago (US)
- Comprehensive Cancer Center Vienna (AT)
- City of Hope (US)
- Azienda Ospedaliera San Gerardo (IT)
- Mayo Clinic in Arizona (US)
- Public Health Ontario (CA)
- Cancer Genetics (United States) (US)
- Istituti di Ricovero e Cura a Carattere Scientifico (IT)
- International Hereditary Cancer Center (PL)
- Beckman Research Institute
- McGill University (CA)
- The Ohio State University (US)
- University of Milano-Bicocca (IT)
- Medical University of Vienna (AT)
- Vanderbilt University Medical Center (US)
- McMaster University (CA)
Publication Details
- Journal
- JNCI Journal of the National Cancer Institute
- Published
- 2025-12-13
- DOI
- https://doi.org/10.1093/jnci/djaf363
- Citations
- 1
- Primary Topic
- BRCA gene mutations in cancer
- Type
- article
- Field-Weighted Citation Impact
- 1.82