Kidney Volume as a Predictor and Modifier of Acute Kidney Injury with Renin-Angiotensin System Inhibitors
We speculate that RAS activation might maintain eGFR by glomerular hyperfiltration in patients with low htTKV. Observed higher incidence of postoperative AKI among RASi users with smaller htTKV for eGFR supports this hypothesis. Withholding RASi before CV surgery might prevent AKI among those with htTKV of 100 ml/m 2 or less.
Authors
- Takayuki Hamano (ORCID: https://orcid.org/0000-0002-2100-9106)
- Takahisa Kasugai (ORCID: https://orcid.org/0009-0000-4445-3878)
- Yosuke Nakai (ORCID: https://orcid.org/0000-0003-2543-9100)
- Tatsuya Tomonari
- Kodai Suzuki (ORCID: https://orcid.org/0000-0003-1861-7394)
- Masashi Mizuno (ORCID: https://orcid.org/0000-0003-3235-6880)
- Yuki Miyaguchi (ORCID: https://orcid.org/0009-0009-3188-4500)
- Miho Murashima (ORCID: https://orcid.org/0000-0002-2923-0438)
- Maki Hiratsuka (ORCID: https://orcid.org/0000-0002-8974-3921)
- Hisao Suda
Institutions
- Nagoya City University (JP)
- Nagoya Medical Center (JP)
- Kindai University (JP)
- The University of Osaka (JP)
Publication Details
- Journal
- Clinical Journal of the American Society of Nephrology
- Published
- 2025-11-26
- DOI
- https://doi.org/10.2215/cjn.0000000911
- Primary Topic
- Acute Kidney Injury Research
- Type
- article
- Field-Weighted Citation Impact
- 0.00