Prostate-specific Antigen Nadir and Time to Nadir Predict Recurrence in Postprostatectomy Patients Treated with Salvage Radiotherapy Without Androgen Deprivation Therapy
Our study showed that the combination of PSA nadir depth and TTN after SRT allows an improvement in prognostic stratification of SRT patients with BCR after RP. These findings might improve patient-tailored decisions between surveillance, active treatment, and treatment escalation.
Authors
- Riccardo Villa (ORCID: https://orcid.org/0000-0003-3040-9061)
- Alessandro Magli (ORCID: https://orcid.org/0000-0002-7004-1938)
- Filippo Alongi (ORCID: https://orcid.org/0000-0002-6569-8628)
- Alessandra Donofrio (ORCID: https://orcid.org/0000-0001-7576-2462)
- Giorgia Timon (ORCID: https://orcid.org/0000-0002-1555-0940)
- Mattia Zaffaroni (ORCID: https://orcid.org/0000-0003-4655-4634)
- Nicola Simoni (ORCID: https://orcid.org/0000-0003-4651-1757)
- Giulio Francolini (ORCID: https://orcid.org/0000-0002-1784-7203)
- Federico Mastroleo (ORCID: https://orcid.org/0000-0001-6580-6767)
- Luca Triggiani (ORCID: https://orcid.org/0000-0003-0168-3432)
- Corrado Spatola (ORCID: https://orcid.org/0000-0001-5562-189X)
- Marcin Miszczyk (ORCID: https://orcid.org/0000-0002-4375-0827)
- Vincenzo Burgio (ORCID: https://orcid.org/0000-0001-9743-446X)
- Ciro Franzese (ORCID: https://orcid.org/0000-0001-6893-6284)
- Maja Hasterok
- Luca Nicosia (ORCID: https://orcid.org/0000-0002-0731-8041)
- Barbara Alicja Jereczek-Fossa
- Salvina Barra
- Giulia Marvaso (ORCID: https://orcid.org/0000-0002-5339-8038)
- Maria Giulia Vincini (ORCID: https://orcid.org/0000-0001-7830-3149)
- Fabio Matrone (ORCID: https://orcid.org/0000-0002-2292-0444)
- Marta Scorsetti (ORCID: https://orcid.org/0000-0003-0320-559X)
- Stefano Arcangeli (ORCID: https://orcid.org/0000-0003-3880-8876)
- Matteo Augugliaro
Institutions
- University of Parma (IT)
- Humanitas University (IT)
- University of Catania (IT)
- Azienda Sanitaria Unità Locale di Reggio Emilia (IT)
- Comprehensive Cancer Center Vienna (AT)
- Ospedale Sacro Cuore Don Calabria (IT)
- Azienda Socio Sanitaria Territoriale degli Spedali Civili di Brescia (IT)
- Azienda Ospedaliero-Universitaria Careggi (IT)
- National Institute of Oncology (HU)
- Centro di Riferimento Oncologico (IT)
- Ospedale Policlinico San Martino (IT)
- The Maria Sklodowska-Curie National Research Institute of Oncology (PL)
- Istituti di Ricovero e Cura a Carattere Scientifico (IT)
- Azienda Ospedaliera Nazionale SS. Antonio e Biagio e Cesare Arrigo (IT)
- IRCCS Humanitas Research Hospital (IT)
- Azienda Sanitaria Universitaria Integrata di Trieste (IT)
- European Institute of Oncology (IT)
- University of Milano-Bicocca (IT)
Publication Details
- Journal
- European Urology Oncology
- Published
- 2025-12-01
- DOI
- https://doi.org/10.1016/j.euo.2025.12.001
- Primary Topic
- Prostate Cancer Diagnosis and Treatment
- Type
- article
- Field-Weighted Citation Impact
- 0.00