Deciphering B Cell Heterogeneity and Pathogenic Mechanisms in Osteoporosis Through Single‐Cell RNA Sequencing

This study underscores the heterogeneity and functions of B cells in osteoporosis, highlighting two signaling pathways implicated in disease progression. These findings offer novel insights into osteoporosis pathogenesis and suggest potential therapeutic targets for its treatment.

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Publication Details

Journal
BioMed Research International
Published
2025-01-01
DOI
https://doi.org/10.1155/bmri/9979105
Primary Topic
Bone Metabolism and Diseases
Type
article
Field-Weighted Citation Impact
0.00
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article

Deciphering B Cell Heterogeneity and Pathogenic Mechanisms in Osteoporosis Through Single‐Cell RNA Sequencing

Jionglin Wu, J F Li, Jiayuan Zheng, Taolve Zhou et al.
BioMed Research International
Bone Metabolism and Diseases
article

Deciphering B Cell Heterogeneity and Pathogenic Mechanisms in Osteoporosis Through Single‐Cell RNA Sequencing

Jionglin Wu, J F Li, Jiayuan Zheng, Taolve Zhou, Yujun Sun, Yanbo Chen, Wenzhou Liu, Guo Fu, Weidong Song, Fan Zhang, Zhenxiang Zheng, Zeng Gang
article en

Abstract

This study underscores the heterogeneity and functions of B cells in osteoporosis, highlighting two signaling pathways implicated in disease progression. These findings offer novel insights into osteoporosis pathogenesis and suggest potential therapeutic targets for its treatment.

BioMed Research InternationalVol. 2025(1)
Sun Yat-sen University (CN), Sun Yat-sen Memorial Hospital (CN)
Openalex Percentile: Top 63%
Bone Metabolism and Diseases
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