Extended Thymectomy via Thoracoscopy and Cervical Incision in a Child with Anterior Mediastinal Mixed Germ Cell Tumor and Paraneoplastic Precocious Puberty

To our knowledge, this case represents the 1st pediatric anterior mediastinal mixed germ cell tumor treated with thoracoscopic extended thymectomy combined with a cervical incision. The approach allowed safe and complete resection despite cranial displacement of the thymus, while avoiding sternotomy. Recognition of endocrine manifestations such as hCG-induced precocious puberty is essential for early diagnosis. This case demonstrates that minimally invasive extended thymectomy with cervical extension is feasible in children and may be applied to achieve radical resection of complex anterior mediastinal tumors.

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Publication Details

Journal
Surgical Case Reports
Published
2025-01-01
DOI
https://doi.org/10.70352/scrj.cr.25-0596
Primary Topic
Myasthenia Gravis and Thymoma
Type
article
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article

Extended Thymectomy via Thoracoscopy and Cervical Incision in a Child with Anterior Mediastinal Mixed Germ Cell Tumor and Paraneoplastic Precocious Puberty

Kenichiro Watanabe, Yousuke Gohda, Hideto Iwafuchi, Masaya Yamoto et al.
Surgical Case Reports
Myasthenia Gravis and Thymoma
article

Extended Thymectomy via Thoracoscopy and Cervical Incision in a Child with Anterior Mediastinal Mixed Germ Cell Tumor and Paraneoplastic Precocious Puberty

Kenichiro Watanabe, Yousuke Gohda, Hideto Iwafuchi, Masaya Yamoto, Akiyoshi Nomura, Yu Sugai, Koji Fukumoto, Hiromu Miyake, Shinichiro Sano
article en

Abstract

To our knowledge, this case represents the 1st pediatric anterior mediastinal mixed germ cell tumor treated with thoracoscopic extended thymectomy combined with a cervical incision. The approach allowed safe and complete resection despite cranial displacement of the thymus, while avoiding sternotomy. Recognition of endocrine manifestations such as hCG-induced precocious puberty is essential for early diagnosis. This case demonstrates that minimally invasive extended thymectomy with cervical extension is feasible in children and may be applied to achieve radical resection of complex anterior mediastinal tumors.

Surgical Case ReportsVol. 11(1)
Osaka City General Hospital (JP), Shizuoka Children's Hospital (JP)
Openalex Percentile: Top 44%
Myasthenia Gravis and Thymoma
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Extended Thymectomy via Thoracoscopy and Cervical Incision in a Child with Anterior Mediastinal Mixed Germ Cell Tumor and Paraneoplastic Precocious Puberty — Kenichiro Watanabe, Yousuke Gohda, et al. · Surgical Case Reports (2025) | TGRS Research Map | TGRS