Reductions in ventilator-associated events following implementation of a ventilator-associated pneumonia diagnostic stewardship intervention: A difference-in-difference study
In this <i>post hoc</i> analysis of a quasi-experimental pilot/feasibility trial, a bundled diagnostic stewardship intervention safely reduced respiratory culturing rates without increasing ventilator-associated events (VAEs). Using difference-in-differences methodology, we observed a significant reduction in possible ventilator-associated pneumonia (PVAP) events, suggesting the intervention may reduce pneumonia overdiagnosis without compromising patient safety.
Authors
- Zachary Garcia
- Andrew Weirauch
- Keith S. Kaye (ORCID: https://orcid.org/0000-0003-2051-1732)
- Krishna Rao (ORCID: https://orcid.org/0000-0002-9213-7850)
- Owen Albin (ORCID: https://orcid.org/0000-0002-1659-4902)
- Emily Stoneman (ORCID: https://orcid.org/0000-0003-2474-826X)
- Jonathan P. Troost (ORCID: https://orcid.org/0000-0002-1183-8330)
- Kevin Thompson
Institutions
- University of Michigan (US)
- Johnson University (US)
- Michigan Medicine (US)
Publication Details
- Journal
- Infection Control and Hospital Epidemiology
- Published
- 2025-12-17
- DOI
- https://doi.org/10.1017/ice.2025.10376
- Primary Topic
- Nosocomial Infections in ICU
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Michigan Institute for Clinical and Health Research