Systematic review and meta‐analysis of antipsychotic discontinuation in dementia
An updated meta-analysis of trials of withdrawal of antipsychotics in dementia.Relative risk of symptom relapse increased when stopping antipsychotics.Relapse risk was not affected by trial design or prior length of treatment.Relapse risk was not affected by length of follow-up, withdrawal speed, or sex.
Authors
- Sophie Roche (ORCID: https://orcid.org/0000-0001-6751-0636)
- Suzanne Reeves (ORCID: https://orcid.org/0000-0001-8053-7024)
- Janneke Scholtz
- Robert Howard (ORCID: https://orcid.org/0000-0002-3071-2338)
- Kathy Liu (ORCID: https://orcid.org/0000-0002-7482-2758)
- Nimesh Naran
Institutions
- St Pancras Hospital (GB)
- The London College (GB)
- University College London (GB)
Publication Details
- Journal
- Alzheimer s & Dementia Translational Research & Clinical Interventions
- Published
- 2025-10-01
- DOI
- https://doi.org/10.1002/trc2.70188
- Primary Topic
- Dementia and Cognitive Impairment Research
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Medical Research Council