Orthopedic manifestations of acquired hemophilia: a case report on uncontrolled bleeding and progressive swelling post-phlebotomy- should fasciotomy be considered?

This case underscores the importance of considering AHA in patients with ACS-like symptoms and unexplained prolonged activated Partial Thromboplastin Time (aPTT), even without bleeding history. It also highlights the need to investigate any unexplained aPTT prolongation before surgical interventions. Collaboration between orthopedic surgeons and hematologists is essential for optimizing outcomes. Approaching to algorithms for non-traumatic ACS in AHA is an important step. Prompt intervention, patient education, and tailored treatment strategies are crucial for preventing severe complications and optimizing patient outcomes.

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Publication Details

Journal
BMC Musculoskeletal Disorders
Published
2025-12-18
DOI
https://doi.org/10.1186/s12891-025-09405-1
Primary Topic
Hemophilia Treatment and Research
Type
article
Field-Weighted Citation Impact
0.00
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article

Orthopedic manifestations of acquired hemophilia: a case report on uncontrolled bleeding and progressive swelling post-phlebotomy- should fasciotomy be considered?

Mehran Mottahedi, Parmida Shahbazi, Elham Nazar, Parham Talebian et al.
BMC Musculoskeletal Disorders
Hemophilia Treatment and Research
article

Orthopedic manifestations of acquired hemophilia: a case report on uncontrolled bleeding and progressive swelling post-phlebotomy- should fasciotomy be considered?

Mehran Mottahedi, Parmida Shahbazi, Elham Nazar, Parham Talebian, Mohammad Soleimani
article en

Abstract

This case underscores the importance of considering AHA in patients with ACS-like symptoms and unexplained prolonged activated Partial Thromboplastin Time (aPTT), even without bleeding history. It also highlights the need to investigate any unexplained aPTT prolongation before surgical interventions. Collaboration between orthopedic surgeons and hematologists is essential for optimizing outcomes. Approaching to algorithms for non-traumatic ACS in AHA is an important step. Prompt intervention, patient education, and tailored treatment strategies are crucial for preventing severe complications and optimizing patient outcomes.

BMC Musculoskeletal DisordersVol. 27(1)
Sina Hospital (IR), Razi Hospital (IR), Tehran University of Medical Sciences (IR)
Openalex Percentile: Top 39%
Hemophilia Treatment and Research
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