FOXM1 Maintains Homeostasis and Self-Renewal in Wharton’s Jelly Mesenchymal Stem Cells
Our findings establish FOXM1 as a critical regulatory node that integrates stem cell identity with proliferative and survival signals to maintain WJ-MSC homeostasis. This study redefines FOXM1's role in stem cell biology and provides a theoretical foundation for enhancing the therapeutic efficacy of WJ-MSCs by modulating this key factor.
Authors
- Nan Li (ORCID: https://orcid.org/0000-0002-8148-1891)
- Qiang Wu (ORCID: https://orcid.org/0000-0003-2049-1639)
Institutions
- Macau University of Science and Technology (MO)
- University of Macau (MO)
Publication Details
- Journal
- Genes
- Published
- 2025-12-18
- DOI
- https://doi.org/10.3390/genes16121517
- Primary Topic
- FOXO transcription factor regulation
- Type
- article
- Field-Weighted Citation Impact
- 0.00