Identification of novel therapeutic targets and effective anticancer agents for gallbladder cancer by integrating bioinformatics analysis and experimental validation
This study identifies potential therapeutic targets for BTC. Drugs designed to target these genes have a higher likelihood of clinical success and are expected to facilitate BTC drug development while reducing associated costs.
Authors
- Rui-Qi Zou
- Ximei Luo
- Fu‐Yu Li (ORCID: https://orcid.org/0000-0003-2755-2887)
- Yanjie Zhong
- Siqi Yang (ORCID: https://orcid.org/0000-0002-7760-9856)
- Zhiqiang He (ORCID: https://orcid.org/0000-0001-8536-5970)
- Hai‐Jie Hu (ORCID: https://orcid.org/0000-0003-2871-290X)
Institutions
- University of Electronic Science and Technology of China (CN)
- Sichuan University (CN)
- West China Hospital of Sichuan University (CN)
- Quzhou University (CN)
Publication Details
- Journal
- Frontiers in Pharmacology
- Published
- 2025-12-18
- DOI
- https://doi.org/10.3389/fphar.2025.1658462
- Primary Topic
- Cholangiocarcinoma and Gallbladder Cancer Studies
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- National Natural Science Foundation of China
- Sichuan University
- Natural Science Foundation of Sichuan Province
- Young Scientists Fund
- West China Hospital, Sichuan University