Synovial Parasitosis and Inflammatory Biomarker Profiles in Osteoarthritis: Associations with Host and Therapeutic Factors

This study highlights a significant prevalence of SP among OPs (57%), with Blastocystis sp. being the most common parasite. CST-treated patients had a higher SP than those with non-CST. Elevated TNF-α and MMP-9 levels could be biomarkers for identifying patients at risk for disease progression due to SP. Further research should be conducted using molecular techniques, along with studies utilizing antiparasitic treatment among infected OA patients.