Novel Synthetic Steroid Derivatives: Target Prediction and Biological Evaluation of Antiandrogenic Activity
The probed efficacy of these novel steroids with respect to spironolactone control appears to be a promising compound for future hormonal therapy with neuroprotection activity in glucose disorder status. However, further research with clinically meaningful endpoints is needed to optimize the use of androgen antagonists in these hormonal therapies in COVID-19 progression.
Authors
- Armando Valenzuela Peraza (ORCID: https://orcid.org/0000-0002-9293-186X)
- Sebastián Cerezo Morales (ORCID: https://orcid.org/0009-0001-4474-615X)
- Rebeca Santes-Palacios (ORCID: https://orcid.org/0000-0001-7310-5178)
- Víctor González-Motos (ORCID: https://orcid.org/0000-0001-7762-272X)
- Maribel Ortíz Herrera (ORCID: https://orcid.org/0000-0002-1515-8164)
- Diego Ortega (ORCID: https://orcid.org/0000-0002-0799-3151)
- Hugo Juárez Olguı́n (ORCID: https://orcid.org/0000-0002-1405-1728)
- Norma Osnaya Brizuela (ORCID: https://orcid.org/0000-0003-0041-3190)
- Alejandra Chávez‐Riveros (ORCID: https://orcid.org/0000-0001-9055-5699)
- Alberto Rojas‐Ochoa (ORCID: https://orcid.org/0000-0002-7115-9882)
- A. Ortiz Velasquez (ORCID: https://orcid.org/0000-0002-4788-7943)
- David Calderón Guzmán (ORCID: https://orcid.org/0000-0002-7373-9389)
- Ernestina Hernández García
Institutions
- Universidad Autónoma Metropolitana (MX)
- Instituto Nacional de Pediatria (MX)
- Universidad Nacional Autónoma de México (MX)
Publication Details
- Journal
- Current Issues in Molecular Biology
- Published
- 2025-12-17
- DOI
- https://doi.org/10.3390/cimb47121059
- Primary Topic
- Estrogen and related hormone effects
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Instituto Nacional de Pediatria