Prognostic value of neutrophil-to-lymphocyte ratio in patients with breast cancer in Ethiopia: using inverse-probability-weighted regression adjustment

A high NLR was associated with significantly higher mortality in BC patients, independent of baseline clinicopathological variables. Patients with elevated NLR more often presented with advanced stage disease and distant metastases. These findings indicate that NLR, a simple and accessible biomarker, may help to identify patients at increased risk of poor prognosis.

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Publication Details

Journal
BMJ Open
Published
2025-12-01
DOI
https://doi.org/10.1136/bmjopen-2025-102933
Primary Topic
Inflammatory Biomarkers in Disease Prognosis
Type
article
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article

Prognostic value of neutrophil-to-lymphocyte ratio in patients with breast cancer in Ethiopia: using inverse-probability-weighted regression adjustment

Berhanetsehay Teklewold, Desalegn Dawit Assele, Binyam Fekadu Desta, Tadele Dana Darebo et al.
BMJ Open
Inflammatory Biomarkers in Disease Prognosis
article

Prognostic value of neutrophil-to-lymphocyte ratio in patients with breast cancer in Ethiopia: using inverse-probability-weighted regression adjustment

Berhanetsehay Teklewold, Desalegn Dawit Assele, Binyam Fekadu Desta, Tadele Dana Darebo, Tinbite Esayas
article en

Abstract

A high NLR was associated with significantly higher mortality in BC patients, independent of baseline clinicopathological variables. Patients with elevated NLR more often presented with advanced stage disease and distant metastases. These findings indicate that NLR, a simple and accessible biomarker, may help to identify patients at increased risk of poor prognosis.

BMJ OpenVol. 15(12)
Hawassa University (ET), Wolaita Sodo University (ET), St. Paul's Hospital Millennium Medical College (ET)
Openalex Percentile: Top 43%
Inflammatory Biomarkers in Disease Prognosis
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