A computational analysis of programmed cell death-associated LncRNA signatures in glioma and drug prediction
This study highlights the prognostic significance of lncRNAs associated with PCD in glioma and provides computational evidence for their potential as therapeutic targets. While the results suggest novel avenues for treatment development, they must be interpreted cautiously due to the lack of experimental validation. Future studies should aim to validate these results through controlled clinical trials and explore underlying molecular mechanisms.
Authors
- Di Tian (ORCID: https://orcid.org/0000-0001-5049-6452)
- Dan Luo (ORCID: https://orcid.org/0000-0001-7105-4485)
- Liyan Jia (ORCID: https://orcid.org/0000-0002-8822-103X)
- Peng Zhang (ORCID: https://orcid.org/0000-0001-8071-3729)
- Wei Liu (ORCID: https://orcid.org/0009-0007-4263-7383)
- Xingyu Liu (ORCID: https://orcid.org/0000-0001-7016-7824)
Institutions
- Weifang Medical University (CN)
- Second Hospital of Shandong University (CN)
Publication Details
- Journal
- BMC Neurology
- Published
- 2025-12-18
- DOI
- https://doi.org/10.1186/s12883-025-04372-5
- Primary Topic
- Cancer-related molecular mechanisms research
- Type
- article
- Field-Weighted Citation Impact
- 0.00