Polyfunctional T peripheral helper cells are associated with the magnitude and durability of antibody responses after COVID‐19
Early S-specific T-cell responses-particularly polyfunctional, IL-21-producing Tph cells-play a key role in sustaining durable antibody levels post-infection, offering insights for future vaccine strategies and understanding long-term immunity.
Authors
- Susan Maddocks
- Vera Merheb
- Kerrie J. Sandgren (ORCID: https://orcid.org/0000-0001-6894-935X)
- Fabienne Brilot (ORCID: https://orcid.org/0000-0002-7025-2276)
- Suat Dervish (ORCID: https://orcid.org/0000-0001-7979-578X)
- Anthony L. Cunningham (ORCID: https://orcid.org/0000-0002-6744-5667)
- Katie Tungatt (ORCID: https://orcid.org/0000-0002-4088-3501)
- Harry Robertson (ORCID: https://orcid.org/0000-0001-9203-3894)
- Stuart Turville (ORCID: https://orcid.org/0000-0003-1918-5343)
- Karen Byth (ORCID: https://orcid.org/0000-0002-1253-6393)
- Rowena Anne Bull (ORCID: https://orcid.org/0000-0002-9844-3744)
- Anupriya Aggarwal (ORCID: https://orcid.org/0000-0001-8678-0519)
- Bruce Taylor (ORCID: https://orcid.org/0000-0003-2807-0070)
- Chloe M. Doyle (ORCID: https://orcid.org/0000-0001-7216-634X)
- Nicole Fewings (ORCID: https://orcid.org/0000-0002-7560-930X)
- Gabriela Martins Costa Gomes (ORCID: https://orcid.org/0000-0002-9807-7211)
- Marianne Martinello (ORCID: https://orcid.org/0000-0001-9444-0186)
- Aija Stubis
Institutions
- The University of Sydney (AU)
- Blacktown & Mount Druitt Hospital (AU)
- Children's Hospital at Westmead (AU)
- Westmead Hospital (AU)
- UNSW Sydney (AU)
- Western NSW Local Health District (AU)
- Prince of Wales Hospital (AU)
- Westmead Institute (AU)
- Sydney Local Health District (AU)
- Westmead Institute for Medical Research (AU)
Publication Details
- Journal
- Clinical & Translational Immunology
- Published
- 2025-01-01
- DOI
- https://doi.org/10.1002/cti2.70070
- Primary Topic
- Psoriasis: Treatment and Pathogenesis
- Type
- article
- Field-Weighted Citation Impact
- 0.00