Comprehensive Dental Rehabilitation in a 6-Year-Old Child with Juvenile Focal Osteoporosis Receiving IV Bisphosphonate Therapy: A Case Report

Pediatric patients receiving intravenous bisphosphonate therapy for juvenile focal osteoporosis present unique challenges for dental management due to concerns about medication-related osteonecrosis of the jaw (MRONJ), despite extremely low documented risk in children. We report the successful comprehensive dental rehabilitation of a 6-year-old child with juvenile focal osteoporosis receiving IV bisphosphonate therapy. Following interdisciplinary consultation with the primary physician and implementation of antibiotic prophylaxis protocols, the patient underwent multiple dental procedures including extractions, pulp therapy, restorations, and stainless-steel crown placement. No complications or signs of MRONJ developed during the 12-month follow-up period. This case demonstrates that comprehensive dental rehabilitation can be safely performed in pediatric patients receiving IV bisphosphonate therapy when evidence-based protocols guide clinical decision-making. Interdisciplinary consultation, antibiotic prophylaxis, and careful monitoring enable successful treatment outcomes while maintaining vigilance for potential complications.

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Publication Details

Journal
Journal of Pharmacy And Bioallied Sciences
Published
2025-12-01
DOI
https://doi.org/10.4103/jpbs.jpbs_1461_25
Primary Topic
Bone health and treatments
Type
article
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article

Comprehensive Dental Rehabilitation in a 6-Year-Old Child with Juvenile Focal Osteoporosis Receiving IV Bisphosphonate Therapy: A Case Report

Rahaf Abdullah Alolayan
Journal of Pharmacy And Bioallied Sciences
Bone health and treatments
article

Comprehensive Dental Rehabilitation in a 6-Year-Old Child with Juvenile Focal Osteoporosis Receiving IV Bisphosphonate Therapy: A Case Report

Rahaf Abdullah Alolayan
article en

Abstract

Pediatric patients receiving intravenous bisphosphonate therapy for juvenile focal osteoporosis present unique challenges for dental management due to concerns about medication-related osteonecrosis of the jaw (MRONJ), despite extremely low documented risk in children. We report the successful comprehensive dental rehabilitation of a 6-year-old child with juvenile focal osteoporosis receiving IV bisphosphonate therapy. Following interdisciplinary consultation with the primary physician and implementation of antibiotic prophylaxis protocols, the patient underwent multiple dental procedures including extractions, pulp therapy, restorations, and stainless-steel crown placement. No complications or signs of MRONJ developed during the 12-month follow-up period. This case demonstrates that comprehensive dental rehabilitation can be safely performed in pediatric patients receiving IV bisphosphonate therapy when evidence-based protocols guide clinical decision-making. Interdisciplinary consultation, antibiotic prophylaxis, and careful monitoring enable successful treatment outcomes while maintaining vigilance for potential complications.

Journal of Pharmacy And Bioallied SciencesVol. 17(Suppl 4)
Qassim University (SA)
Openalex Percentile: Top 44%
Bone health and treatments
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Comprehensive Dental Rehabilitation in a 6-Year-Old Child with Juvenile Focal Osteoporosis Receiving IV Bisphosphonate Therapy: A Case Report — Rahaf Abdullah Alolayan · Journal of Pharmacy And Bioallied Sciences (2025) | TGRS Research Map | TGRS