Temporal trends and regional disparities in prostate cancer mortality in the United States, 1999–2023: an analysis of the CDC WONDER database

From 1999 to 2023, prostate cancer mortality among U.S. men aged 45 years and older showed a consistent decline. While the AAMR continued to decrease, the rate of decline slowed after 2013, likely due to changes in prostate-specific antigen (PSA) screening practices. In contrast, the observed rise in the absolute number of deaths mainly reflects demographic effects associated with population aging. The greatest burdens were observed among residents of the South, NH Black men, older adults, and rural populations. State-level AAMRs revealed a clear geographic gradient, with consistently higher rates in the South and lower rates in the Northeast. These findings highlight the need for future prevention and control strategies to prioritize high-risk groups through targeted interventions that promote health equity.

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Publication Details

Journal
BMC Public Health
Published
2025-12-18
DOI
https://doi.org/10.1186/s12889-025-25694-6
Citations
1
Primary Topic
Prostate Cancer Diagnosis and Treatment
Type
article
Field-Weighted Citation Impact
1.52

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article

Temporal trends and regional disparities in prostate cancer mortality in the United States, 1999–2023: an analysis of the CDC WONDER database

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1 citations
BMC Public Health
Prostate Cancer Diagnosis and Treatment
1.52
article

Temporal trends and regional disparities in prostate cancer mortality in the United States, 1999–2023: an analysis of the CDC WONDER database

Jianbin Zhou, Zhifang Chai, Zheng Dong, Yi‐Ming Fan, Sheng Li, Haolin Li, Peng Gu, Zhiwei He, XinQi Dong, Shuangfeng Yan, Pengxiang Lei
article en
1 citations

Abstract

From 1999 to 2023, prostate cancer mortality among U.S. men aged 45 years and older showed a consistent decline. While the AAMR continued to decrease, the rate of decline slowed after 2013, likely due to changes in prostate-specific antigen (PSA) screening practices. In contrast, the observed rise in the absolute number of deaths mainly reflects demographic effects associated with population aging. The greatest burdens were observed among residents of the South, NH Black men, older adults, and rural populations. State-level AAMRs revealed a clear geographic gradient, with consistently higher rates in the South and lower rates in the Northeast. These findings highlight the need for future prevention and control strategies to prioritize high-risk groups through targeted interventions that promote health equity.

BMC Public HealthVol. 25(1)
Kunming Medical University (CN), First Affiliated Hospital of Kunming Medical University (CN)
National Natural Science Foundation of China, Kunming Medical University, Centers for Disease Control and Prevention
Openalex Percentile: Top 12%
Prostate Cancer Diagnosis and Treatment
1.52
DOIOpen Access PDFOpenAlex
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