Association between quality of life and inflammation and fibrosis markers in primary biliary cholangitis over three-year follow-up
In Danish PBC patients, one-third had impaired QoL, primarily due to fatigue. QoL was reduced in cirrhosis but preserved in earlier fibrosis stages. Higher sCD163 was independently associated with lower physical QoL, particularly among UDCA non-responders.
Authors
- Lars Bossen (ORCID: https://orcid.org/0000-0003-4641-4500)
- Holger Jon Møller (ORCID: https://orcid.org/0000-0001-7687-5995)
- Anders Mellemkjær (ORCID: https://orcid.org/0000-0002-1909-9990)
- Peter Holland‐Fischer (ORCID: https://orcid.org/0000-0002-6082-3338)
- Henning Grønbæk (ORCID: https://orcid.org/0000-0001-8998-7910)
- Jesper Bach Hansen
- Matias Hauge Böttcher (ORCID: https://orcid.org/0009-0005-3793-0935)
Institutions
- Aarhus University (DK)
- Aalborg University Hospital (DK)
- Aarhus University Hospital (DK)
Publication Details
- Journal
- Scandinavian Journal of Gastroenterology
- Published
- 2025-12-17
- DOI
- https://doi.org/10.1080/00365521.2025.2602520
- Primary Topic
- Liver Diseases and Immunity
- Type
- article
- Field-Weighted Citation Impact
- 0.00