Development of a consensus extension of the estimands framework for cluster randomised trials (CRT-estimands): results from an international Delphi study
This Delphi identified expert consensus around the importance of several key items for defining estimands in cluster randomised trials. These results can inform the development of consensus guidance outlining the set of attributes to describe when defining estimands for cluster randomised trials.
Authors
- Catherine L. Auriemma (ORCID: https://orcid.org/0000-0003-4803-0375)
- Brennan C Kahan (ORCID: https://orcid.org/0000-0001-9957-0844)
- Andrew J Copas (ORCID: https://orcid.org/0000-0001-8968-5963)
- Professor Gary S. Collins (ORCID: https://orcid.org/0000-0002-2772-2316)
- Frank Bretz (ORCID: https://orcid.org/0000-0002-2008-8340)
- Michael O. Harhay (ORCID: https://orcid.org/0000-0002-0553-674X)
- Dongquan Bi (ORCID: https://orcid.org/0000-0001-5234-302X)
- Melanie Bahti (ORCID: https://orcid.org/0009-0008-6998-5289)
- Fan Li (ORCID: https://orcid.org/0000-0001-6183-1893)
Institutions
- Novartis (Switzerland) (CH)
- Statistics Austria (AT)
- Yale University (US)
- MRC Clinical Trials Unit at UCL (GB)
- NIHR Birmingham Biomedical Research Centre (GB)
- University College London (GB)
- Medical University of Vienna (AT)
- University of Pennsylvania (US)
- University of Birmingham (GB)
Publication Details
- Journal
- Trials
- Published
- 2025-12-18
- DOI
- https://doi.org/10.1186/s13063-025-09352-1
- Primary Topic
- Delphi Technique in Research
- Type
- article
- Field-Weighted Citation Impact
- 0.00