Osteoprogenitor cells from non-regenerative bone show greater resistance to cellular stress than those from regenerative bone
Together, these findings suggest that periosteal cells exhibit intrinsic differences based on anatomical location, which may influence their regenerative capacity and contribute to different healing outcomes.
Authors
- Joshua A. Broussard (ORCID: https://orcid.org/0000-0002-3752-7880)
- Alexander J. Trostle (ORCID: https://orcid.org/0000-0001-5028-0184)
- Tyrel Long
- Robert J. Tower (ORCID: https://orcid.org/0000-0001-5856-5758)
- Jennifer Simkin (ORCID: https://orcid.org/0000-0002-6122-4222)
- Mimi C. Sammarco (ORCID: https://orcid.org/0000-0001-9491-5735)
- Sylvia Culpepper
Institutions
- University of Kentucky (US)
- Mayo Clinic in Arizona (US)
- Louisiana State University Health Sciences Center New Orleans (US)
- The University of Texas Southwestern Medical Center (US)
Publication Details
- Journal
- Frontiers in Cell and Developmental Biology
- Published
- 2025-12-18
- DOI
- https://doi.org/10.3389/fcell.2025.1684670
- Primary Topic
- Mesenchymal stem cell research
- Type
- article
- Field-Weighted Citation Impact
- 0.00