Mitophagy-related gene TRIP13 predicts prognosis and immune response and promotes proliferation and migration in vitro and in vivo of clear cell renal cell carcinoma
The prognosis and immune response of patients with ccRCC could be reliably estimated by the model in our cohorts created using MRGs in this research. The development of ccRCC is significantly influenced by MRGs, particularly TRIP13. This study can assist in offering ccRCC patients individualized treatment options.
Authors
- Qiyu Xiao
- Guanglan Chen
- Yinzi Liu (ORCID: https://orcid.org/0000-0002-4888-1746)
- Luo Wen (ORCID: https://orcid.org/0000-0003-3927-3340)
- Lanlan Wang (ORCID: https://orcid.org/0009-0001-5982-3592)
- Ying Fu (ORCID: https://orcid.org/0000-0002-3805-1028)
- Lian Guo (ORCID: https://orcid.org/0000-0001-9109-7546)
- Zhongjun Jiang
- Zuping He (ORCID: https://orcid.org/0000-0003-3741-9350)
Institutions
- Central South University (CN)
- Zunyi Medical University (CN)
- Hunan Cancer Hospital (CN)
- University of South China (CN)
Publication Details
- Journal
- Frontiers in Pharmacology
- Published
- 2025-12-18
- DOI
- https://doi.org/10.3389/fphar.2025.1736086
- Primary Topic
- Autophagy in Disease and Therapy
- Type
- article
- Field-Weighted Citation Impact
- 0.00