Cecal growth factors promote enteric neurosphere formation and hindgut colonization in the avian model
These findings support the neurosphere-forming potential of avian ENSCs and identify ceca-derived signals (GDNF, WNT11, ET-3) and Noggin as potent regulators of ENS progenitor maintenance and differentiation.
Authors
- K. Kocsis (ORCID: https://orcid.org/0000-0001-7033-6552)
- Viktória Halasy (ORCID: https://orcid.org/0000-0002-1713-5986)
- Ádám Soós (ORCID: https://orcid.org/0000-0002-1660-3303)
- Emőke Szőcs (ORCID: https://orcid.org/0000-0002-7724-5474)
- Jitka Mucksová (ORCID: https://orcid.org/0000-0002-0636-3537)
- Nándor Nagy (ORCID: https://orcid.org/0000-0002-6223-5214)
- Fruzsina Mógor (ORCID: https://orcid.org/0000-0001-6897-1311)
- Jiřı́ Hejnar (ORCID: https://orcid.org/0000-0002-2362-6677)
- Csenge Jurenka
- Zsanna Gecse
Institutions
- Semmelweis University (HU)
- Institute of Molecular Genetics (RU)
- Czech Academy of Sciences, Institute of Molecular Genetics (CZ)
- BIOPHARM (Czechia) (CZ)
Publication Details
- Journal
- Frontiers in Cell and Developmental Biology
- Published
- 2025-12-18
- DOI
- https://doi.org/10.3389/fcell.2025.1681844
- Primary Topic
- Congenital gastrointestinal and neural anomalies
- Type
- article
- Field-Weighted Citation Impact
- 0.00