Anti-inflammatory effect of a pimarane diterpenoid isolated from Nepeta adenophyta Hedge based on a network analysis approach and experimental assessment
The present study indicates that compound <b>1</b> shows a significant anti-inflammatory effect, potentially through intervention in the NF-κB and PPARγ signaling pathways.
Authors
- Wei Zhao (ORCID: https://orcid.org/0000-0002-4177-8105)
- Iftikhar Ali (ORCID: https://orcid.org/0000-0002-5817-8800)
- Changku Jia (ORCID: https://orcid.org/0000-0002-6613-295X)
- Menghe H. Li (ORCID: https://orcid.org/0000-0001-7028-7092)
- Long Chen (ORCID: https://orcid.org/0000-0002-8451-1419)
Institutions
- Qilu University of Technology (CN)
- Heilongjiang University of Chinese Medicine (CN)
- Karakoram International University (PK)
- Shandong Academy of Sciences (CN)
- Shandong Academy of Chinese Medicine (CN)
Publication Details
- Journal
- Frontiers in Pharmacology
- Published
- 2025-12-18
- DOI
- https://doi.org/10.3389/fphar.2025.1652902
- Primary Topic
- Bioactive Natural Diterpenoids Research
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Shandong Academy of Sciences
- Qilu University of Technology