Duodenal Tumor Presenting With Persistent Vomiting: Diagnostic and Therapeutic Challenges

Duodenal tumors are rare neoplasms of the small intestine, often diagnosed at an advanced stage due to nonspecific clinical presentation and diagnostic challenges. We present the case of a 40-year-old patient hospitalized for vomiting, abdominal pain, and unintentional weight loss. During hospitalization, a duodenal mass was diagnosed, along with multiple liver metastases and associated gastrointestinal obstruction. This report discusses the epidemiology, pathogenesis, classification, clinical presentation, diagnostic methods, and therapeutic strategies for duodenal tumors, with particular emphasis on progressive intestinal obstruction and the need for appropriate nutritional interventions. This case highlights the importance of early diagnosis and an interdisciplinary approach in managing this rare disease.

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Publication Details

Journal
Cureus
Published
2025-12-17
DOI
https://doi.org/10.7759/cureus.99506
Primary Topic
Gastrointestinal Tumor Research and Treatment
Type
article
Field-Weighted Citation Impact
0.00
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article

Duodenal Tumor Presenting With Persistent Vomiting: Diagnostic and Therapeutic Challenges

Katarzyna Bielawska, Aleksandra Tlak, Wiktoria J Auguścik
Cureus
Gastrointestinal Tumor Research and Treatment
article

Duodenal Tumor Presenting With Persistent Vomiting: Diagnostic and Therapeutic Challenges

Katarzyna Bielawska, Aleksandra Tlak, Wiktoria J Auguścik
article en

Abstract

Duodenal tumors are rare neoplasms of the small intestine, often diagnosed at an advanced stage due to nonspecific clinical presentation and diagnostic challenges. We present the case of a 40-year-old patient hospitalized for vomiting, abdominal pain, and unintentional weight loss. During hospitalization, a duodenal mass was diagnosed, along with multiple liver metastases and associated gastrointestinal obstruction. This report discusses the epidemiology, pathogenesis, classification, clinical presentation, diagnostic methods, and therapeutic strategies for duodenal tumors, with particular emphasis on progressive intestinal obstruction and the need for appropriate nutritional interventions. This case highlights the importance of early diagnosis and an interdisciplinary approach in managing this rare disease.

CureusVol. 17(12)
National Centre for Nuclear Research (PL), Grochowski Hospital (PL)
Openalex Percentile: Top 42%
Gastrointestinal Tumor Research and Treatment
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