Association of Peripheral Blood Neutrophil‐Lymphocyte Ratio With Motor and Cognitive Function in Prodromal Parkinson's Disease
Our findings indicate that higher NLR, largely reflecting reduced lymphocyte levels, is already present in the prodromal phase of PD and relates to the severity of motor symptoms. Prospective longitudinal studies are needed to clarify whether NLR has predictive value for progression to overt PD.
Authors
- Nyeonju Kang (ORCID: https://orcid.org/0000-0003-4440-4413)
- Kyeongho Byun (ORCID: https://orcid.org/0000-0001-8072-1876)
- Ryul Kim (ORCID: https://orcid.org/0000-0002-8754-9180)
- Kiwon Park (ORCID: https://orcid.org/0000-0002-3188-000X)
- Jin‐Sun Jun (ORCID: https://orcid.org/0000-0001-9879-0634)
Institutions
- Incheon National University (KR)
- Seoul Metropolitan Government (KR)
- Hallym University Kangnam Sacred Heart Hospital (KR)
- Korea National Sport University (KR)
Publication Details
- Journal
- Brain and Behavior
- Published
- 2025-12-01
- DOI
- https://doi.org/10.1002/brb3.71141
- Primary Topic
- Parkinson's Disease Mechanisms and Treatments
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Bristol-Myers Squibb
- Eli Lilly and Company
- Biogen
- Celgene
- Jazz Pharmaceuticals
- National Research Foundation
- H. Lundbeck A/S
- Ministry of Science and ICT, South Korea
- Genentech
- Allergan
- Avid Radiopharmaceuticals