An intelligent diagnosis method for thyroid nodules using UNet++ integrated with ResNet and transformer

The diagnosis of thyroid nodules usually relies on the professional experience of physicians, which can easily lead to misdiagnosis and missed diagnoses. This paper introduces an intelligent diagnosis model for thyroid nodules, building upon a hybrid framework of U-Net and residual networks. Experimental results show that the average diagnostic accuracy of this model for the thyroid gland in the TN-SCUI 2020 dataset (4554 images, with a ratio of 8:1:1 for training set, validation set and test set) is greater than 92%, and the highest single-class accuracy rate reaches 95%. At the same time, the Dice index and Jaccard index of the model in the TN3K dataset (3493 images, with a ratio of 8:1:1 for training set, validation set and test set) can reach up to 86.16% and 85.28%, and the diagnostic accuracy is improved by 6% compared to the baseline model. The novelty of this article lies in the deep integration of U-shaped network++, residual network, and Transformer, which fills the gap in global semantic modeling and dynamic weight optimization. However, the proposed model still needs prospective clinical validation, and its adaptability to complex scenarios needs to be improved. In the future, more external validations and lightweight experiments will be conducted.

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Publication Details

Journal
Discover Artificial Intelligence
Published
2025-12-18
DOI
https://doi.org/10.1007/s44163-025-00738-3
Primary Topic
Thyroid Cancer Diagnosis and Treatment
Type
article
Field-Weighted Citation Impact
0.00
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article

An intelligent diagnosis method for thyroid nodules using UNet++ integrated with ResNet and transformer

Minghui Guo
Discover Artificial Intelligence
Thyroid Cancer Diagnosis and Treatment
article

An intelligent diagnosis method for thyroid nodules using UNet++ integrated with ResNet and transformer

Minghui Guo
article en

Abstract

The diagnosis of thyroid nodules usually relies on the professional experience of physicians, which can easily lead to misdiagnosis and missed diagnoses. This paper introduces an intelligent diagnosis model for thyroid nodules, building upon a hybrid framework of U-Net and residual networks. Experimental results show that the average diagnostic accuracy of this model for the thyroid gland in the TN-SCUI 2020 dataset (4554 images, with a ratio of 8:1:1 for training set, validation set and test set) is greater than 92%, and the highest single-class accuracy rate reaches 95%. At the same time, the Dice index and Jaccard index of the model in the TN3K dataset (3493 images, with a ratio of 8:1:1 for training set, validation set and test set) can reach up to 86.16% and 85.28%, and the diagnostic accuracy is improved by 6% compared to the baseline model. The novelty of this article lies in the deep integration of U-shaped network++, residual network, and Transformer, which fills the gap in global semantic modeling and dynamic weight optimization. However, the proposed model still needs prospective clinical validation, and its adaptability to complex scenarios needs to be improved. In the future, more external validations and lightweight experiments will be conducted.

Discover Artificial IntelligenceVol. 6(1)
Yangtze University (CN)
Openalex Percentile: Top 47%
Thyroid Cancer Diagnosis and Treatment
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