Effect of hemodialysis on high-sensitivity cardiac troponin T levels in patients with hypervolemia

In ESKD patients with hypervolemia, a single HD session using a high-flux dialyzer significantly increased hs-cTnT plasma level. Pre-dialysis hs-cTnT measurements should be used as a clinical baseline when evaluating for ACS, and post-dialysis elevations should be interpreted with caution. Serial measurements may improve diagnostic accuracy. Further prospective studies are needed to clarify the mechanisms and clinical implications of these findings.

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Publication Details

Journal
Frontiers in Nephrology
Published
2025-12-18
DOI
https://doi.org/10.3389/fneph.2025.1717448
Primary Topic
Acute Myocardial Infarction Research
Type
article
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article

Effect of hemodialysis on high-sensitivity cardiac troponin T levels in patients with hypervolemia

Mohammad Tinawi, Bahar Bastani
Frontiers in Nephrology
Acute Myocardial Infarction Research
article

Effect of hemodialysis on high-sensitivity cardiac troponin T levels in patients with hypervolemia

Mohammad Tinawi, Bahar Bastani
article en

Abstract

In ESKD patients with hypervolemia, a single HD session using a high-flux dialyzer significantly increased hs-cTnT plasma level. Pre-dialysis hs-cTnT measurements should be used as a clinical baseline when evaluating for ACS, and post-dialysis elevations should be interpreted with caution. Serial measurements may improve diagnostic accuracy. Further prospective studies are needed to clarify the mechanisms and clinical implications of these findings.

Frontiers in NephrologyVol. 5
Indiana University Northwest (US), Saint Louis University (US)
Openalex Percentile: Top 42%
Acute Myocardial Infarction Research
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