Fibrinogen supplementation enhances antivenom efficacy in treating coagulopathy due to hemotoxic snakebite envenoming by Trimeresurus and Agkistrodon species in Yunnan, China
These findings suggest that adjunctive Fg supplementation may improve the laboratory parameters of coagulopathy and reduce the length of hospital stay in hemotoxic snakebite envenoming. However, further clinical evaluations are needed to support the use of Fg as an adjuvant in the management of hemotoxic snakebite envenoming.
Authors
- Zengzheng Li (ORCID: https://orcid.org/0000-0003-3333-6267)
- Shuai Feng
- Qiuqi Gao
- Qingting Huang (ORCID: https://orcid.org/0000-0002-9488-5983)
- Bin Han (ORCID: https://orcid.org/0000-0001-7867-6797)
- Y K Onno Teng (ORCID: https://orcid.org/0000-0001-9920-2195)
- Yibin Wang (ORCID: https://orcid.org/0000-0003-0852-0767)
- Yaming Wang (ORCID: https://orcid.org/0000-0002-8208-8696)
Institutions
- Kunming University of Science and Technology (CN)
- Xuzhou Medical College (CN)
- First People's Hospital of Yunnan Province (CN)
- The People's Hospital of LinXia (CN)
- Xuzhou No.1 People's Hospital (CN)
Publication Details
- Journal
- Frontiers in Medicine
- Published
- 2025-12-18
- DOI
- https://doi.org/10.3389/fmed.2025.1667800
- Primary Topic
- Venomous Animal Envenomation and Studies
- Type
- article
- Field-Weighted Citation Impact
- 0.00