Predicting cerebral infarction in COPD patients: an individualized nomogram based on arterial oxygen saturation

COPD is prone to cerebral infarction, and we verified the relationship between COPD and cerebral infarction through a visualogram model. The incidence of cerebral infarction in COPD patients is affected by systemic immune-inflammatory index (SII), age, hypertension, cardiovascular disease (C), hemiplegia, and SaO<sub>2</sub>, and the nomogram model for risk prediction based on SaO<sub>2</sub> has good predictive efficacy, which can provide a reference forbral infarction in COPD patients in clinical practice. However, this study was retrospective, the sample size of the different subtypes of ischemic stroke was small, the risk analysis of each subtype of ischemic stroke could not be performed, and there may be some unmeasured confounding factors, which had a certain impact on the of the study. In the future, we need multi-center prospective studies to verify the effectiveness and practicality of the nomogram, and the basic mechanism of each risk factor also to be studied.

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Publication Details

Journal
Frontiers in Medicine
Published
2025-12-18
DOI
https://doi.org/10.3389/fmed.2025.1675147
Primary Topic
Chronic Obstructive Pulmonary Disease (COPD) Research
Type
article
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article

Predicting cerebral infarction in COPD patients: an individualized nomogram based on arterial oxygen saturation

Riken Chen, Sihan Lin, Weimin Yao, Guangbin Liang et al.
Frontiers in Medicine
Chronic Obstructive Pulmonary Disease (COPD) Research
article

Predicting cerebral infarction in COPD patients: an individualized nomogram based on arterial oxygen saturation

Riken Chen, Sihan Lin, Weimin Yao, Guangbin Liang, Qinghua Chen, Yuli Cai, Xing Li, Bao‐Guo Xiao, Zheqian Chen, Lijuan Zeng, Feiju Chen, Huimin Chen, Xin Chen, Xinyao Liu, J. Pan, Deyi Zhou, Jun Cheng
article en

Abstract

COPD is prone to cerebral infarction, and we verified the relationship between COPD and cerebral infarction through a visualogram model. The incidence of cerebral infarction in COPD patients is affected by systemic immune-inflammatory index (SII), age, hypertension, cardiovascular disease (C), hemiplegia, and SaO<sub>2</sub>, and the nomogram model for risk prediction based on SaO<sub>2</sub> has good predictive efficacy, which can provide a reference forbral infarction in COPD patients in clinical practice. However, this study was retrospective, the sample size of the different subtypes of ischemic stroke was small, the risk analysis of each subtype of ischemic stroke could not be performed, and there may be some unmeasured confounding factors, which had a certain impact on the of the study. In the future, we need multi-center prospective studies to verify the effectiveness and practicality of the nomogram, and the basic mechanism of each risk factor also to be studied.

Frontiers in MedicineVol. 12
Guangdong Medical College (CN), Guangdong Pharmaceutical University (CN), Second Affiliated Hospital of Guangzhou Medical University (CN), Guangzhou Medical University (CN)
Openalex Percentile: Top 41%
Chronic Obstructive Pulmonary Disease (COPD) Research
DOIOpen Access PDFOpenAlex
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