<i> <b>Candida albicans</b> </i> <b>is a context-dependent risk factor for malignant transformation of oral precancer lesions: a prospective cohort study of 734 Taiwanese patients</b>
High <i>Candida albicans</i> burden is a significant, subtype-dependent risk factor for malignant progression in OPMDs. These findings underline the role of fungal-host interactions in oral carcinogenesis and support the integration of fungal profiling into routine surveillance of OPMDs.
Authors
- I‐Shou Chang (ORCID: https://orcid.org/0000-0002-6254-8114)
- Wen‐Lun Wang (ORCID: https://orcid.org/0000-0002-4623-4385)
- Yen‐Tze Liu (ORCID: https://orcid.org/0000-0002-5922-2295)
- Tze‐Ta Huang (ORCID: https://orcid.org/0000-0001-6774-7182)
- Shine‐Gwo Shiah (ORCID: https://orcid.org/0000-0002-1003-973X)
- Yi‐Ping Hsieh (ORCID: https://orcid.org/0000-0002-8218-2228)
- Shih Sheng Jiang (ORCID: https://orcid.org/0000-0003-1909-437X)
- Li-Hsin Chien
- Chun-Yi Chuang
- I‐Chi Chen (ORCID: https://orcid.org/0000-0002-8576-0521)
- Chih-Chun Wang
- Yi‐Chieh Chen (ORCID: https://orcid.org/0000-0002-8307-0666)
- Pei-Hua Wu
- Tsung-Te Chung
- Jang‐Jaer Lee (ORCID: https://orcid.org/0000-0003-0964-0840)
- Mu‐Kuan Chen (ORCID: https://orcid.org/0000-0002-6242-1842)
- Chung‐Hsing Chen (ORCID: https://orcid.org/0000-0002-1205-7368)
- Ya‐Wen Chen (ORCID: https://orcid.org/0000-0002-6080-8859)
- Ko‐Jiunn Liu
- Fang-Yu Tsai
- Shun-Fa Yang
- Ching‐Yu Yen
Institutions
- National Chung Hsing University (TW)
- National Health Research Institutes (TW)
- National Taiwan University (TW)
- National Dong Hwa University (TW)
- E-Da Hospital (TW)
- Chung Shan Medical University Hospital (TW)
- Chang Bing Show Chwan Memorial Hospital (TW)
- National Taiwan University Hospital (TW)
- Chi Mei Medical Center (TW)
- National Cheng Kung University Hospital (TW)
- Changhua Christian Hospital (TW)
- Taipei Medical University (TW)
- Chung Shan Medical University (TW)
- National Cheng Kung University (TW)
- I-Shou University (TW)
Publication Details
- Journal
- Journal of Oral Microbiology
- Published
- 2025-12-17
- DOI
- https://doi.org/10.1080/20002297.2025.2598743
- Primary Topic
- Antifungal resistance and susceptibility
- Type
- article
- Field-Weighted Citation Impact
- 0.00