Association of the triglyceride glucose–body roundness index with mortality in HFpEF and effect modification by nutritional status: a multicenter prospective cohort study
In patients with HFpEF, the TyG-BRI was independently associated with adverse outcomes, with its prognostic value particularly evident among those with impaired nutritional status. Incorporating the TyG-BRI into the risk model modestly improved prognostic discrimination, and reduced exercise capacity appeared to partly mediate this association.
Authors
- Bingqiang Li (ORCID: https://orcid.org/0000-0003-3746-2113)
- You Zhou (ORCID: https://orcid.org/0000-0002-0779-9519)
- Yingli Xie
- Ruixiao Chen
- Zhaokun Pu
- Jindong Zhao (ORCID: https://orcid.org/0000-0003-0005-1820)
- Yanhui Han (ORCID: https://orcid.org/0000-0002-1908-7674)
- Huifeng Zhang (ORCID: https://orcid.org/0009-0005-3499-7325)
- Hengliang Zhang (ORCID: https://orcid.org/0000-0002-8174-7215)
- Liping Wang (ORCID: https://orcid.org/0000-0001-9355-1167)
Institutions
- First Affiliated Hospital of Henan University of Science and Technology (CN)
Publication Details
- Journal
- Lipids in Health and Disease
- Published
- 2025-12-18
- DOI
- https://doi.org/10.1186/s12944-025-02834-w
- Primary Topic
- Nutrition and Health in Aging
- Type
- article
- Field-Weighted Citation Impact
- 0.00