Tolvaptan pharmacokinetics and pharmacodynamics in adolescents with autosomal dominant polycystic kidney disease
• This report presents the pharmacokinetics and pharmacodynamic effects of tolvaptan in adolescents with ADPKD and compares the pharmacodynamic effects to untreated adolescents.
Authors
- Kimberly Sikes
- Susan E. Shoaf (ORCID: https://orcid.org/0000-0001-7725-9385)
Institutions
- Otsuka Pharmaceutical (Spain) (ES)
Publication Details
- Journal
- European Journal of Pediatrics
- Published
- 2025-12-18
- DOI
- https://doi.org/10.1007/s00431-025-06689-2
- Primary Topic
- Genetic and Kidney Cyst Diseases
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Otsuka Pharmaceutical