Dose-Dependent Effects of Intratesticular Adipose-Derived Mesenchymal Stem Cell Injection on Heat-Induced Spermatogenesis Disorder in Wistar Rats: Focus on Apoptosis and Oxidative Stress
A single dose-dependent injection of AMSCs demonstrated regenerative properties that improved with increasing cell number. Overall, administration of 1×10⁶ AMSCs can alleviate testicular damage and promote the spermatogenesis process in testicular hyperthermia.
Authors
- Mona Saheli (ORCID: https://orcid.org/0000-0001-7517-0117)
- Saeedeh Shojaeepour (ORCID: https://orcid.org/0000-0003-1327-1400)
- Shahriar Dabiri (ORCID: https://orcid.org/0000-0002-5922-3976)
- Masoud Imani (ORCID: https://orcid.org/0000-0002-5882-5043)
- Maryam Arbabi Dastgerd
- Reza Bahramnezhad
Institutions
- Shahid Bahonar University of Kerman (IR)
- Kerman University of Medical Sciences (IR)
Publication Details
- Journal
- Iranian journal of pathology
- Published
- 2025-12-18
- DOI
- https://doi.org/10.30699/ijp.2025.2063503.3477
- Primary Topic
- Sperm and Testicular Function
- Type
- article
- Field-Weighted Citation Impact
- 0.00