Gaining extensive resistance against clubroot disease through the disruption of a susceptibility gene
This Commentary examines research by Wu et al. showing that β-1,3-glucan synthase-like 5 (GSL5) functions as a key gene for susceptibility to clubroot in Brassica family members by suppressing immunity regulated by jasmonic acid. Inaction of GSL5 through genome editing provides broad-spectrum resistance to clubroot.
Authors
- Qibin Wu (ORCID: https://orcid.org/0000-0002-3600-7613)
- Youxiong Que (ORCID: https://orcid.org/0000-0003-1111-5834)
- Zhen Zeng (ORCID: https://orcid.org/0000-0001-5680-7047)
- Zheng-Qing Fu (ORCID: https://orcid.org/0000-0003-1519-6192)
- Daowen Wang (ORCID: https://orcid.org/0000-0002-6230-8735)
Institutions
- Chinese Academy of Tropical Agricultural Sciences (CN)
- University of South Carolina (US)
- Henan Agricultural University (CN)
Publication Details
- Journal
- Journal of Integrative Plant Biology
- Published
- 2025-12-17
- DOI
- https://doi.org/10.1111/jipb.70119
- Primary Topic
- Plant Disease Resistance and Genetics
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- National Science Foundation