Dengue serotypes and epidemic dynamics in Brazil: a spatiotemporal perspective

Changes in the geographic distribution and territorial expansion of Aedes aegypti, the main dengue vector in the Americas, coupled with the concurrent circulation of multiple DENV serotypes, have driven the overall rise in dengue incidence in Brazil. Here, we investigate the spatiotemporal distribution of dengue virus serotypes across Brazil, focusing on dengue epidemiology over the last decade (2014-2025). We examine the temporal dynamics of these serotypes and discuss the main strategies to mitigate the public health impact of their co-circulation.