Uterine epithelial estrogen receptor α temporally regulates preimplantation uterine immunity involving interleukin-1β signaling
These findings demonstrate an essential function of uterine epithelial ERα in controlling mating-induced inflammation in the LE layer, stromal layer, and uterine lumen, and highlight the IL-1β signaling pathway among the molecular mechanisms involved in regulation of uterine inflammation by uterine epithelial ERα.
Authors
- Yuehuan Li (ORCID: https://orcid.org/0000-0001-8836-0198)
- Wendy T. Watford (ORCID: https://orcid.org/0000-0003-4261-5399)
- Tong Zhou (ORCID: https://orcid.org/0000-0003-2361-1931)
- Xiaoqin Ye
- Declan Gresham
- Jonathan Matthew Hancock
- Taylor Elijah Martin
- Skyler Owens-Gonzalez
Institutions
- University of Nevada, Reno (US)
- University of Georgia (US)
- South China Institute of Collaborative Innovation (CN)
Publication Details
- Journal
- Reproductive and Developmental Medicine
- Published
- 2025-12-17
- DOI
- https://doi.org/10.1097/rd9.0000000000000149
- Primary Topic
- Reproductive System and Pregnancy
- Type
- article
- Field-Weighted Citation Impact
- 0.00