Robustness of time-domain near-infrared spectroscopy against skin pigmentation differences
We systematically demonstrate skin pigmentation negligibly affects TD-NIRS results (optical properties, hemodynamic parameters) through in-vivo (static, dynamic, campaign on pediatric cohort) and phantom measurements, proving its robustness in retrieving tissue saturation in clinical settings.
Authors
- Mauro Buttafava (ORCID: https://orcid.org/0000-0002-5446-8026)
- Alessandro Torricelli (ORCID: https://orcid.org/0000-0002-6878-8936)
- Caterina Amendola (ORCID: https://orcid.org/0000-0002-6738-9589)
- Alessandro Bossi (ORCID: https://orcid.org/0009-0004-9232-5124)
- Vamshi Damagatla (ORCID: https://orcid.org/0000-0003-4140-387X)
- Michele Lacerenza (ORCID: https://orcid.org/0000-0002-8214-9882)
- Davide Contini (ORCID: https://orcid.org/0000-0003-1209-9397)
- Gianvincenzo Zuccotti (ORCID: https://orcid.org/0000-0002-2795-9874)
- Valeria Calcaterra (ORCID: https://orcid.org/0000-0002-2137-5974)
- Virginia Rossi (ORCID: https://orcid.org/0000-0001-8363-9210)
- Lorenzo Spinelli (ORCID: https://orcid.org/0000-0002-4414-4351)
- Ilaria Bargigia (ORCID: https://orcid.org/0000-0003-4428-7958)
- Sara Zanelli (ORCID: https://orcid.org/0009-0005-7112-0522)
- Fabio Negretti (ORCID: https://orcid.org/0009-0003-0620-2703)
Institutions
- University of Milan (IT)
- University of Pavia (IT)
- Istituto di Fotonica e Nanotecnologie (IT)
- Center for Nano Science and Technology (IT)
- Ospedale dei Bambini Vittore Buzzi (IT)
- Politecnico di Milano (IT)
Publication Details
- Published
- 2025-12-17
- DOI
- https://doi.org/10.1117/12.3098387
- Primary Topic
- Optical Imaging and Spectroscopy Techniques
- Type
- article
- Field-Weighted Citation Impact
- 0.00