Panaxadiol saponins-loaded gel for periodontitis therapy: anti-inflammatory and microbiota-modulating effects
PDS gel can inhibit the MAPK/NF-κB pathway-mediated inflammatory response, reduce bone destruction, and regulate bacterial dysbiosis, demonstrating good therapeutic prospects for periodontitis.
Authors
- Xiaohui Wei (ORCID: https://orcid.org/0000-0001-9105-5186)
- Liang Feng (ORCID: https://orcid.org/0000-0003-4807-7480)
- Shusheng Lai
- Xin Zeng (ORCID: https://orcid.org/0000-0002-4180-3366)
- Ming Chen (ORCID: https://orcid.org/0000-0001-5041-9342)
- Zhengtao Wang (ORCID: https://orcid.org/0000-0003-2797-4625)
- H. C. Shi (ORCID: https://orcid.org/0009-0009-1349-586X)
Institutions
- Nanjing University of Chinese Medicine (CN)
- Guangxi University (CN)
- Shanghai University of Traditional Chinese Medicine (CN)
- Tiandi Science & Technology (China) (CN)
Publication Details
- Journal
- Drug Development and Industrial Pharmacy
- Published
- 2025-12-17
- DOI
- https://doi.org/10.1080/03639045.2025.2604647
- Primary Topic
- Ginseng Biological Effects and Applications
- Type
- article
- Field-Weighted Citation Impact
- 0.00